Destination guide

Mediterranean cruises

Historic cities, island ports and very different embarkation points make the route matter. Compare Mediterranean ports, sea days and departure cities, then choose the ship that fits.

Find your cruise

Compare the route, departure port and ship. Select a cruise to see its ports on the map.

748 matching itineraries

  • Virgin Voyages

    French Riviera, Italy & Ibiza Overnight

    Valiant Lady · 6 nights

    From Barcelona

  • Virgin Voyages

    Italy, French Riviera & Spain

    Valiant Lady · 6 nights

    From Barcelona

  • MSC Cruises

    Marmaris, Naples, Civitavecchia, Santorini, Marmaris

    MSC Divina · 6 nights

    From Marmaris

  • MSC Cruises

    Italy, Greece, Turkey

    MSC Divina · 6 nights

    From Rome (Civitavecchia)

  • MSC Cruises

    Marmaris, Naples, Civitavecchia, Mykonos, Marmaris

    MSC Divina · 6 nights

    From Marmaris

  • MSC Cruises

    Naples, Palermo, La Goulette, Barcelona, Marseille, Genoa

    MSC Euribia · 6 nights

    From Naples

  • MSC Cruises

    Cagliari, Civitavecchia, Livorno, Cannes, Palma de Mallorca, Barcelona

    MSC Fantasia · 6 nights

    From Cagliari

  • MSC Cruises

    Civitavecchia, Livorno, Cannes, Palma de Mallorca, Barcelona, Marseille

    MSC Fantasia · 6 nights

    From Rome (Civitavecchia)

  • MSC Cruises

    Piraeus, Kusadasi, Istanbul, Corfu, Bari, Trieste

    MSC Fantasia · 6 nights

    From Athens (Piraeus)

  • MSC Cruises

    Italy, Spain

    MSC Fantasia · 6 nights

    From Rome (Civitavecchia)

  • MSC Cruises

    Italy, Greece

    MSC Lirica · 6 nights

    From Venice

  • MSC Cruises

    Venice-Marghera, Corfu, Civitavecchia, Valencia

    MSC Lirica · 6 nights

    From Venice

Plan the route

What makes a Mediterranean itinerary good?

Mediterranean itineraries can cover very different regions. Compare the actual ports, port hours, sea days and embarkation city before price. A route focused on Italy and the western Mediterranean feels very different from one built around Greece, Turkey and the eastern Mediterranean.

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Plan your time ashore

Find your port

Open a port guide for day plans, arrival advice, transport, practical information and tours.

148 ports

Explore this destination on the map →

Where cruises begin

Mediterranean departure ports

Your embarkation port affects flight logistics, the first and last day of the trip, and which Mediterranean regions a ship can comfortably reach.

Alicante · Ancona · Arles · Athens (Piraeus) · Barcelona · Bari · Bordeaux · Brindisi · Cagliari · Cannes · Genoa · Giurgiu · Istanbul · Izmir · Kusadasi (Ephesus) · La Goulette (Tunis) · La Spezia (Tuscany) · Livorno (Florence and Pisa) · Lyon · Málaga · Marmaris · Marseille · Messina (Sicily) · Naples · Palermo · Palma de Mallorca · Ravenna · Rome (Civitavecchia) · Split · Tarragona · Trieste · Valencia · Valletta · Venice (Fusina)

Choose the experience

Then choose the ship

Once the route works, compare ship size, space per passenger, crew ratios, dining, pools and what the fare actually includes.

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Mediterranean cruise FAQ
How long is a typical Mediterranean cruise?

Seven-night sailings are common, with longer itineraries combining more countries or regions. Compare the day-by-day route and port hours rather than choosing on length alone.

Western or eastern Mediterranean?

Western routes often feature Spain, France and Italy, while eastern routes commonly emphasize Greece, Croatia and Turkey. The actual ports and time ashore matter more than the regional label.

Which Mediterranean departure port should I choose?

Barcelona, Rome-area Civitavecchia, Athens-area Piraeus and other ports can anchor very different routes. Consider flights, pre-cruise time and the day-by-day itinerary together.

Can I explore Mediterranean ports independently?

Often, yes, but some headline sights are far from the cruise terminal. Check each port guide for transportation, timing and whether an independent day is practical.