Itineraries / 15-Night Panama Canal Eastward Your journey, day by day Choose a day to explore the port and follow the route.
≈ Day 2 At sea
≈ Day 3 At sea
≈ Day 5 At sea
≈ Day 6 At sea
≈ Day 8 At sea
≈ Day 10 At sea
11 Day 11 Panama Canal (Cruising), Panama
≈ Day 13 At sea
≈ Day 15 At sea
Day 1 · United States
San Diego Embarkation
San Diego docks downtown at the Embarcadero, so the USS Midway, the Gaslamp Quarter and the waterfront are all on foot. Balboa Park and the zoo are a short ride and need most of a day between them.
San Diego port guide → See the complete schedule Day by day itinerary Day Port 1 San Diego United States 2 At sea 3 At sea 4 Puerto Vallarta Mexico 5 At sea 6 At sea 7 Puerto Quetzal Guatemala 8 At sea 9 Puntarenas Costa Rica 10 At sea 11 Panama Canal (Cruising), Panama 12 Cartagena Colombia 13 At sea 14 George Town Cayman Islands 15 At sea 16 Tampa United States
The map illustrates the route. Port times, where supplied, may change. Follow the ship’s all-aboard deadline on the day.
Dining Entertainment Cabins
Dining on Serenade of the Seas Explore the ship guide for the available dining information and photos.
Explore the ship → Entertainment on Serenade of the Seas Explore the ship guide for the available entertainment information and photos.
Explore the ship → Cabins on Serenade of the Seas Explore the ship guide for the available cabins information and photos.
Explore the ship → What Royal Caribbean includes → Historical averages from NASA POWER . Check a forecast near departure.
Schedule supplied 2026-10-04. Ports and times are subject to change; the cruise line confirms the final itinerary.
Your sailing
Let’s get this cruise booked DepartureOctober 7, 2027 From $2,269 per person
Checked October 4, 2026 Let’s get this cruise booked Cabin categories, per person Inside $2,269 Oceanview $2,498
Final fare, inclusions and cabin availability are confirmed as we arrange your booking.
Serenade of the Seas October 7, 2027
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